Keith Urban and Little Big Town have been tapped to perform at this year’s Stand Up to Cancer telethon. The two acts will be joined by superstar Celine Dion; all three have recently lost a loved one to the ravaging disease.

The annual fundraising event, produced by Bradley Cooper, will also include appearances by Ben Affleck, Matthew McConaughey, Emma Stone, Anna Kendrick, Eric Stonestreet, Alison Sweeny and SU2C Co-Founder Katie Couric, among others.

Stand Up to Cancer is set to air live from The Music Center’s Walt Disney Concert Hall in LA September 9th at 8pm ET on several channels, including ABC, CBS, NBC, Fox, TBS, Bravo, HBO, Great American Country, STARZ and VH1.